• In the largest published case

  2019-04-23

  

  In the largest published case series, Rossi et al. identified seven cases of infant B-ALL, including three cases of congenital leukemia, with lineage switch from B-lymphoid to myelomonocytic leukemia [12]. An additional two cases were described with a switch from AML M5 to B-ALL. Of the nine describ

• We have received funding from

  2019-04-23

  

  We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid

• br Materials and methods br Conflict of interest

  2019-04-23

  

  Materials and methods Conflict of interest statement Acknowledgements This work was supported by the National Natural Science Foundation of China (No: 31100781); the Natural Science Foundation of Hebei Province, PR China (No: C2011206040); and the Department of Health of Hebei Province (No:

• br Historical overview Before the development of screw in

  2019-04-23

  

  Historical overview Before the development of screw-in leads, several types of non-screw pacing leads were designed to passively attach to the Cy5.5 NHS ester muscle with tips of different shapes, including straight, fringed, finned, or tined. However, a high incidence of dislodgement was a majo

• Two months from the initiation of

  2019-04-22

  

  Two months from the initiation of dasatinib, abnormal FDG uptake of the left femur tumor had disappeared. Examination of peripheral blood and the bone marrow examination showed that a complete cytogenetic response was achieved and a ratio of BCR-ABL to ABL on the international scale was 0.21%. Her d

• inhibitor of catalase br Dissemination permissive characteri

  2019-04-22

  

  Dissemination-permissive characteristics of the BM vascular niche Sinusoids (type L capillaries) are the most abundant blood vessels in bone and widely distributed throughout the bone marrow cavity [8]. Sinusoids in bone are discontinuous single layer of endothelial inhibitor of catalase devoid o

• ERS and BrS are thought to represent

  2019-04-22

  

  ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural buy 1-Deoxynojirimycin disease and occasionally to sudden infant death synd

• br Should child growth replace diarrhoea as the

  2019-04-22

  

  Should child growth replace diarrhoea as the primary child health outcome for sanitation trials? We appreciate Derek Headey\'s comment in relation to our trial that the window of opportunity to plausibly affect growth faltering is from in utero up to 24 months, and therefore that sanitation trials

• Bennet and colleagues also make an important addition to the

  2019-04-22

  

  Bennet and colleagues also make an important addition to the literature on the Affordable Medicines Facility—malaria (AMFm) intervention, since a comparison of ACT treatment coverage for countries that had the AMFm intervention is made with those for countries that did not have the AMFm intervention

• Notwithstanding issues of equity improvement of research

  2019-04-22

  

  Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o

• alk pathway br Case report A year old man with dilated

  2019-04-20

  

  Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200

• br Method br Results br Discussion The present evaluation of

  2019-04-20

  

  Method Results Discussion The present evaluation of ΔFCL in chronic AF patients over a long-term observation tnf alpha revealed a few interesting findings. First, at the end of the 6-year observation period, the mean FCL had prolonged from 154±20ms to 187±37ms in patients with ARB therapy

• Bone marrow resident Macs Osteomacs are located

  2019-04-20

  

  Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow enba and they differ fr

• La ignorancia que evidencia Xa

  2019-04-20

  

  La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l

• Universalisation means reaching all individuals with good qu

  2019-04-20

  

  Universalisation means reaching all individuals with good quality, effective interventions without financial hardship. Coverage matters. Participatory women\'s groups are effective in reducing newborn mortality among poor populations provided they involve about 30% of pregnant women in the populatio

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