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br Universalismo cosmopolitismo y pol ticas culturales La co
2019-05-21

Universalismo, cosmopolitismo y políticas culturales La conciencia universalista y el cosmopolitismo han sido productos de los movimientos y de los intercambios cada vez más acelerados de nuestro mundo. Desde las expansiones mercantiles y católicas del siglo xvi, los parámetros y los referentes a
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According to most published reports patients
2019-05-21

According to most published reports, patients with Twiddler\'s syndrome are usually diagnosed due to some type of sudden device malfunction [1–4,6–15]. Early detection of this condition can also be achieved with a home monitoring system [8]. The case presented is a rare one in which Twiddler\'s synd
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br Methods We reviewed http www canadiancancertrials ca and
2019-05-21

Methods We reviewed http://www.canadiancancertrials.ca/ and http://www.ontario.canadiancancertrials.ca/ in order to identify ongoing bone oncology-related trials. We used the keywords: bone, bone metastasis, bone treatment, cancer therapy induced bone loss and bisphosphonates for searching. We al
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Bisphosphonates are a well established standard of care trea
2019-05-21

Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated
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br Results Compared to the respective untreated groups the V
2019-05-21

Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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Autophagy can be generally divided into
2019-05-21

Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein ache in
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The great American epidemiologist Bill
2019-05-21

The great American epidemiologist Bill Silverman taught us that the road to hell is paved with good intentions. From 1942, during a 12-year period, more than 10 000 infants were blinded through retinopathy of prematurity because paediatricians recommended a minor increase in the concentration of sup
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Commission on Global Surgery s vision is universal access to
2019-05-21

Commission on Global Surgery\'s vision is “universal access to safe, affordable surgical and anaesthesia care when needed”. 5 billion people, largely the poor, marginalised, and rural, face impossible hurdles and for all practical purposes are excluded from what is often life-saving or disability-av
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opioid receptors Este autor nos permite la oportunidad de re
2019-05-21

Este autor nos permite la oportunidad de reflexionar la presencia de los sujetos colectivos a la hora de elaborar proyectos ético-políticos de la llamada “sociedad por venir”. Por ejemplo, cabe destacar en sus propuestas la preocupación sobre la justicia de las personas y de los colectivos desde la
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Situaci n que aparece como un tema de
2019-05-21

Situación que aparece como un tema de reflexión filosófica, tanto por los discursos que produce tal situación descrita como por las cuestiones éticas que suscita, por ejemplo: el problema ético de la justicia en tanto que los pueblos originarios no han sido objeto de ella desde las políticas moderna
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br Discussion Appendicitis is seen in the general
2019-05-21

Discussion Appendicitis is seen in the general population with a lifetime cumulative incidence rate of 9% [7]. Our calculated incidence rate of appendicitis in the setting of acute leukemia (1.9%) correlates with the reported incidence of 0.5–4.4% [1]. Leukemic involvement of the gastrointestinal
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Interpretation Stakeholders from sectors not historically en
2019-05-21

Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North
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The Zika virus epidemic is spreading countries are now repor
2019-05-21

The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil
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Heat shock facilitates the folding of various proteins as me
2019-05-20

Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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Although the long term stability
2019-05-20

Although the long-term stability of childhood intelligence during the life course has been shown in longitudinal studies, studies of the long-term effects of breastfeeding are important. With age, the effects of early developmental factors might either be diluted, because of the effects of later env
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