• The ultrafiltration approach has been used to measure

  2020-08-19

  

  The ultrafiltration approach has been used to measure equilibrium BIEs for a number of enzyme systems, including LY2603618 receptor hexokinase (Lewis and Schramm, 2003a, Lewis and Schramm, 2003b), thymidine phosphorylase (Birck & Schramm, 2004), purine nucleoside phosphorylase (Murkin, Tyler, & Sch

• Herein the interactions of etamicastat nepicastat and zamica

  2020-08-18

  

  Herein, the interactions of etamicastat, nepicastat and zamicastat with P-gp and BCRP were evaluated. Although recent investigations have been performed to assess the involvement of P-gp in the Netilmicin Sulfate exposure of nepicastat and etamicastat (Loureiro et al., 2015), the contribution of BC

• Nanocomposite films with a GNP DNA filler concentration

  2020-08-18

  

  Nanocomposite films with a GNP-DNA filler concentration of 20 wt%, 30 wt%, and 40 wt% were investigated by electrical impedance spectroscopy before and after UV-C irradiation (Fig. 2). EIS data were fitted to a RC-circuit model and surface resistivity values were calculated from the fitted resistanc

• Acknowledgment This work was supported by

  2020-08-18

  

  Acknowledgment This work was supported by the Swedish Research Council, the Knut and Alice Wallenberg Foundation, the Göran Gustafsson Foundation, the Swedish Pain Relief Foundation, the Torsten Söderbergs Stiftelse, the Swedish Children\'s Cancer Foundation, and the Swedish Cancer Society. The

• CaneCPI showed strong inhibitory activity against recombinan

  2020-08-18

  

  CaneCPI-4 showed strong inhibitory activity against recombinant falcipain-2 and falcipain-3, with IC values of 11.9±0.4nM and 42.3±0.8nM, respectively (Table 1, Supplementary material). Falcipains are involved in hemoglobin cleavage, with generation of two fractions: the heme and the globin. The hem

• br Conflict of interest statement br Acknowledgement The stu

  2020-08-18

  

  Conflict of interest statement Acknowledgement The study was financially supported by the Ministry of Education, Youth and Sports of the Czech Republic – projects “CENAKVA” (No. CZ.1.05/2.1.00/01.0024) and “CENAKVA II” (No. LO1205 under the NPU I program), by the Grant Agency of the University

• CXC chemokines are primarily expressed in immune organs

  2020-08-18

  

  CXC chemokines are primarily expressed in immune organs and the central nervous system: the mouse thymus and spleen (Heesen et al., 1996), chicken bursa (Liang et al., 2001), primate (Macaca mulatta) pyruvate dehydrogenase kinase inhibitor (Federsppiel et al., 1993) and cattle locus coeruleus, cere

• The heterogeneity among studies that investigated the associ

  2020-08-18

  

  The heterogeneity among studies that investigated the association of COMT Val158Met with alexithymia was also significant (Ham et al., 2005; Min et al., 2016; Swart et al., 2011; Zekioglu et al., 2014). The healthy status, drug effect, and other demographic variables also influenced one\'s ability o

• The heterogeneity among studies that investigated the associ

  2020-08-18

  

  The heterogeneity among studies that investigated the association of COMT Val158Met with alexithymia was also significant (Ham et al., 2005; Min et al., 2016; Swart et al., 2011; Zekioglu et al., 2014). The healthy status, drug effect, and other demographic variables also influenced one\'s ability o

• Progesterone s metabolite THP may also be mediating

  2020-08-18

  

  Progesterone\'s metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, FLAG tag australia and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans

• br Materials and methods br Results br Discussion

  2020-08-18

  

  Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor Anti-cancer Compound Library recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carci

• br Halogenases Enzymatic C H activation leading

  2020-08-18

  

  Halogenases Enzymatic C–H activation leading to halogenation is another emerging area in biocatalysis [55,56]. Incorporation of halogen atoms during medicinal chemistry eff ;orts is a well-established practice, presenting an effective means to control the molecule’s bioactivity and physicochemical

• The mesolimbic dopamine system is believed to be

  2020-08-17

  

  The mesolimbic dopamine system is believed to be highly important for evaluating environmental stimuli in order to generate an adaptive behavioral response. Thus, not surprisingly these functions appear to have been highly conserved across the vertebrate subphylum. Even though teleost fish lack midb

• RDH belongs to C family of

  2020-08-17

  

  RDH10 belongs to 16C family of the short-chain dehydrogenase/reductase (SDRs) superfamily of proteins [12], [13]. Notably, in human genome adjacent to the gene encoding RDH10 on chromosome 8 are located two other genes encoding members of the SDR16C family: retinol dehydrogenase epidermal 2 (RDHE2,

• Our recent QTL mapping study revealed

  2020-08-17

  

  Our recent QTL mapping study revealed that the adaptor genes, including the NCK genes and the ABI genes, are located within the genomic regions harboring the most significant QTL (Zhou et al., 2017), suggesting that these genes could be involved in the determination of resistance, and possibly throu

9981 records 418/666 page Previous Next First page 上5页 416417418419420 下5页 Last page